Metabolic highway

Follow a drug from the moment it enters the body until the last of it leaves: what it turns into, which enzyme does the work, how long each step takes, and whether each new molecule still has an effect.

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Every step is cited to Wikipedia, journals and TripSit.

HeroinHeroin → 6-MAM → Morphine → M3G CodeineCodeine → Morphine → Norcodeine → Glucuronides TramadolTramadol → O-DSMT → Other metabolites → Urine CocaineCocaine → Benzoylecgonine → Norcocaine → + alcohol: cocaethylene MDMAMDMA → HHMA → HMMA → MDA DiazepamDiazepam → Nordazepam → Temazepam → Oxazepam AlcoholEthanol → Acetaldehyde → Acetate → CO₂ + water PsilocybinPsilocybin → Psilocin → Psilocin-O-glucuronide → 4-HIAA and others

Made by readers

Built by readers with the timeline maker and checked by staff against their sources before going up. They are kept apart from the site’s own write-ups.

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From Wikipedia (1155)

Metabolism, metabolites, half-life and excretion as each Wikipedia infobox records them, plus metabolites the article text names plainly, linked to the revision used.

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Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.