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Acebutolol

What the body does with Acebutolol, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

AcebutololtakenDiacetololmetaboliteExitRenal: 30%; Biliary: 60%

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    40% (range 35 to 50%) 1

  2. hoursbreakdown

    Metabolism

    Hepatic 1

  3. hoursfrom the article text

    What else it turns into

    “Diacetolol is the primary metabolite of acebutolol.” 2

  4. half-lifehalf gone

    Elimination half-life

    3-4 hours (parent drug); 8-13 hours (active metabolite) 1

  5. exitleaves the body

    Excretion

    Renal: 30%; Biliary: 60% 1

Sources

  1. Wikipedia, Acebutolol, drug infobox (revision 1329237940), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
  2. Wikipedia, Diacetolol, article text (revision 1374881341), CC BY-SA 4.0. Sentences quoted as they appear.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.