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Risperidone

What the body does with Risperidone, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

RisperidonetakenPaliperidonemetaboliteExitUrinary (70%) feces (14%)

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    70% (by mouth) 1

  2. hoursbreakdown

    Metabolism

    Liver (CYP2D6 mediated to 9-hydroxyrisperidone) 1

  3. hoursfrom the article text

    What else it turns into

    “Risperidone and its metabolite paliperidone are reduced in efficacy by P-glycoprotein inducers such as St John's wort” 2

  4. half-lifehalf gone

    Elimination half-life

    20 hours (by mouth), 3–6 days (IM) 1

  5. exitleaves the body

    Excretion

    Urinary (70%) feces (14%) 1

Sources

  1. Wikipedia, Risperidone, drug infobox (revision 1378635584), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
  2. Wikipedia, Paliperidone, article text (revision 1369113631), CC BY-SA 4.0. Sentences quoted as they appear.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.