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Lapatinib

What the body does with Lapatinib, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

LapatinibtakenExitMostly Feces

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    Variable, increased with food 1

  2. hoursbreakdown

    Metabolism

    Liver, mostly CYP3A-mediated (minor 2C19 and 2C8 involvement) 1

  3. half-lifehalf gone

    Elimination half-life

    24 hours (repeated dosing), 14.2 hours (single dose) 1

  4. exitleaves the body

    Excretion

    Mostly Feces 1

Source

  1. Wikipedia, Lapatinib, drug infobox (revision 1358386166), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.