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Aspirin

What the body does with Aspirin, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

AspirintakenExitUrine (80–100%), sweat, saliva, feces

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    80–100% 1

  2. hoursbreakdown

    Metabolism

    Liver (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall. 1

  3. half-lifehalf gone

    Elimination half-life

    Dose-dependent; 2–3 h for low doses (100 mg or less), 15–30 h for larger doses. 1

  4. exitleaves the body

    Excretion

    Urine (80–100%), sweat, saliva, feces 1

Source

  1. Wikipedia, Aspirin, drug infobox (revision 1378675444), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.