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Doxepin

What the body does with Doxepin, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

DoxepintakenNordoxepinmetaboliteExitKidney: ~50%; Feces: minor

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    13–45% (mean 29%) 1

  2. hoursbreakdown

    Metabolism

    Liver (CYP2D6, CYP2C19) 1

  3. hoursmade from it

    Metabolites

    Nordoxepin, glucuronide conjugates 1

  4. half-lifehalf gone

    Elimination half-life

    Doxepin: 8–24 hours (mean 17 hours); Nordoxepin: 28–31 hours 1

  5. exitleaves the body

    Excretion

    Kidney: ~50%; Feces: minor 1

Source

  1. Wikipedia, Doxepin, drug infobox (revision 1357572789), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.