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Etretinate

What the body does with Etretinate, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

EtretinatetakenAcitretinmetabolite

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. hoursmade from it

    Metabolites

    Free acid, Z-form, chain shortening 1

  2. hoursfrom the article text

    What else it turns into

    “Acitretin is a metabolite of etretinate, which was used prior to the introduction of acitretin.” 2

  3. half-lifehalf gone

    Elimination half-life

    120 days 1

Sources

  1. Wikipedia, Etretinate, drug infobox (revision 1341590172), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
  2. Wikipedia, Acitretin, article text (revision 1366318727), CC BY-SA 4.0. Sentences quoted as they appear.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.