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Phenytoin

What the body does with Phenytoin, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

PhenytointakenExitUrinary (23–70%), bile

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    10–30 min (intravenous) 1

  2. doseabsorbed

    Bioavailability

    70–100% (oral), 24.4% (rectal) 1

  3. hoursbreakdown

    Metabolism

    Liver 1

  4. half-lifehalf gone

    Elimination half-life

    10–22 hours 1

  5. durationeffects

    Duration of action

    24 hours 1

  6. exitleaves the body

    Excretion

    Urinary (23–70%), bile 1

Source

  1. Wikipedia, Phenytoin, drug infobox (revision 1371791164), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.