intoxicant.wiki2catechol4school
← All metabolic timelinesMetabolic highway

GHB

What the body does with GHB, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

GHBtakenExit1–5%, kidney

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    Within 5–15 minutes 1

  2. doseabsorbed

    Bioavailability

    25% (oral) 1

  3. hoursbreakdown

    Metabolism

    95–98%, mainly liver, also in blood and tissues 1

  4. hoursmade from it

    Metabolites

    Succinic semialdehyde, Succinic acid 1

  5. half-lifehalf gone

    Elimination half-life

    30–60 minutes 1

  6. exitleaves the body

    Excretion

    1–5%, kidney 1

Source

  1. Wikipedia, Γ-Hydroxybutyric acid, drug infobox (revision 1375974367), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.