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Lidocaine

What the body does with Lidocaine, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

LidocainetakenExitKidney

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    Within 1.5 min (IV) 1

  2. doseabsorbed

    Bioavailability

    35% (by mouth); 3% (topical) 1

  3. hoursbreakdown

    Metabolism

    Liver, 90% CYP3A4-mediated 1

  4. half-lifehalf gone

    Elimination half-life

    1.5 h to 2 h 1

  5. durationeffects

    Duration of action

    10 min to 20 min (IV), 0.5 h to 3 h (local) 1

  6. exitleaves the body

    Excretion

    Kidney 1

Source

  1. Wikipedia, Lidocaine, drug infobox (revision 1378817110), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.