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Febuxostat

What the body does with Febuxostat, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

FebuxostattakenExitUrine (~49%, mostly as metabolites, 3% a

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    ≥84% absorbed 1

  2. hoursbreakdown

    Metabolism

    via CYP1A1, 1A2, 2C8, 2C9, UGT1A1, 1A8, 1A9 1

  3. half-lifehalf gone

    Elimination half-life

    ~5–8 hours 1

  4. exitleaves the body

    Excretion

    Urine (~49%, mostly as metabolites, 3% as unchanged drug); feces (~45%, mostly as metabolites, 12% as unchanged drug) 1

Source

  1. Wikipedia, Febuxostat, drug infobox (revision 1360922496), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.