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Amphotericin B

What the body does with Amphotericin B, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

Amphotericin BtakenExit40% found in urine after single cumulate

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    100% (IV) low (oral) 1

  2. hoursbreakdown

    Metabolism

    kidney 1

  3. half-lifehalf gone

    Elimination half-life

    Initial phase: 24 hours; Second phase: approximately 15 days 1

  4. exitleaves the body

    Excretion

    40% found in urine after single cumulated over several days; Biliary excretion is also important 1

Source

  1. Wikipedia, Amphotericin B, drug infobox (revision 1358547003), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.