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Selexipag

What the body does with Selexipag, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

SelexipagtakenExit93% faeces

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    49% 1

  2. hoursbreakdown

    Metabolism

    Activation by carboxylesterases, inactivation by CYP2C8 and others 1

  3. hoursmade from it

    Metabolites

    ACT-333679, the free acid (active metabolite) 1

  4. half-lifehalf gone

    Elimination half-life

    0.8–2.5 h (selexipag) and 6.2–13.5 h (ACT-333679) 1

  5. exitleaves the body

    Excretion

    93% faeces 1

Source

  1. Wikipedia, Selexipag, drug infobox (revision 1329368752), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.