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Prasterone

What the body does with Prasterone, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

PrasteronetakenAndrosteronemetaboliteEtiocholanolonemetaboliteAndrostenedionemetaboliteAndrostenediolmetaboliteTestosteronemetaboliteEstronemetaboliteEstradiolmetabolitePrasterone sulfatemetaboliteExitUrine

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    50% 1

  2. hoursbreakdown

    Metabolism

    Liver 1

  3. hoursmade from it

    Metabolites

    Androsterone; Etiocholanolone; DHEA sulfate; Androstenedione; Androstenediol; Testosterone; Dihydrotestosterone; Androstanediol; Estrone; Estradiol 1

  4. hoursfrom the article text

    What else it turns into

    “Prasterone is also reversibly transformed into its active metabolite prasterone sulfate (DHEA-S) by steroid sulfotransferase (specifically SULT1E1 and SULT2A1), which in turn can be converted back into prasterone by steroid sulfatase.” 2

  5. half-lifehalf gone

    Elimination half-life

    DHEA: 25 minutes; DHEA-S: 11 hours 1

  6. exitleaves the body

    Excretion

    Urine 1

Sources

  1. Wikipedia, Prasterone, drug infobox (revision 1371931160), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
  2. Wikipedia, Prasterone, article text (revision 1371931160), CC BY-SA 4.0. Sentences quoted as they appear.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.