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Desloratadine

What the body does with Desloratadine, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

DesloratadinetakenExit40% as conjugated metabolites into urine

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    within 1 hour 1

  2. doseabsorbed

    Bioavailability

    Rapidly absorbed 1

  3. hoursbreakdown

    Metabolism

    UGT2B10, CYP2C8 1

  4. hoursmade from it

    Metabolites

    3-Hydroxydesloratadine 1

  5. half-lifehalf gone

    Elimination half-life

    27 hours, 33.7 hours in elderly patients 1

  6. durationeffects

    Duration of action

    up to 24 hours 1

  7. exitleaves the body

    Excretion

    40% as conjugated metabolites into urine; Similar amount into the feces 1

Source

  1. Wikipedia, Desloratadine, drug infobox (revision 1357378936), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.