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Minoxidil

What the body does with Minoxidil, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

MinoxidiltakenExitUrine: >97% (10–15% unchanged; within 12

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    Oral: 30–60 minutes (peak); Sublingual: 30 minutes 1

  2. doseabsorbed

    Bioavailability

    Oral: ≥90% (absorption); Topical: ~1.2–1.4% 1

  3. hoursbreakdown

    Metabolism

    Primarily liver via glucuronidation, hydroxylation, and sulfation (SULT1A1, SULT2A1) 1

  4. hoursmade from it

    Metabolites

    Minoxidil glucuronide; Minoxidil sulfate 1

  5. half-lifehalf gone

    Elimination half-life

    Oral: 3–4 hours; Topical: 22 hours 1

  6. durationeffects

    Duration of action

    Oral: ~72 hours; Topical: 10–12 hours 1

  7. exitleaves the body

    Excretion

    Urine: >97% (10–15% unchanged; within 12–20 hours for oral and 4 days for topical) 1

Source

  1. Wikipedia, Minoxidil, drug infobox (revision 1378723349), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.