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Alprazolam

What the body does with Alprazolam, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

AlprazolamtakenExitKidney

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    30–60 minutes 1

  2. doseabsorbed

    Bioavailability

    80–90% 1

  3. hoursbreakdown

    Metabolism

    Liver, via cytochrome P450 3A4 1

  4. hoursmade from it

    Metabolites

    α-hydroxyalprazolam; 4-hydroxyalprazolam 1

  5. half-lifehalf gone

    Elimination half-life

    IR dosing: 11–13 hours; ER dosing: 11–16 hours 1

  6. durationeffects

    Duration of action

    IR dosing: 6 hours; ER dosing: 11.3 hours 1

  7. exitleaves the body

    Excretion

    Kidney 1

Source

  1. Wikipedia, Alprazolam, drug infobox (revision 1369242307), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.