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Sertindole
What the body does with Sertindole, from the dose to the exit, as its Wikipedia drug infobox records it.
Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.
SertindoletakenExitFaecal (the majority), Kidney (4% metabo
The clock, on a log scale
Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.
- doseabsorbed
Bioavailability
75% 1
- hoursbreakdown
Metabolism
Liver (mostly via CYP2D6 and CYP3A4) 1
- half-lifehalf gone
Elimination half-life
3 days 1
- exitleaves the body
Excretion
Faecal (the majority), Kidney (4% metabolites; 1% unchanged) 1
Source
- Wikipedia, Sertindole, drug infobox (revision 1362889706), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.