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Cinacalcet

What the body does with Cinacalcet, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

CinacalcettakenExitRenal (80%) and fecal (15%)

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    20 to 25%; increases if taken with food 1

  2. hoursbreakdown

    Metabolism

    Hepatic (CYP3A4-, CYP2D6- and CYP1A2-mediated) 1

  3. half-lifehalf gone

    Elimination half-life

    30 to 40 hours 1

  4. exitleaves the body

    Excretion

    Renal (80%) and fecal (15%) 1

Source

  1. Wikipedia, Cinacalcet, drug infobox (revision 1333584314), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.