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Warfarin
What the body does with Warfarin, from the dose to the exit, as its Wikipedia drug infobox records it.
Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.
WarfarintakenExitKidney (92%)
The clock, on a log scale
Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.
- doseabsorbed
Bioavailability
79–100% (by mouth) 1
- hoursbreakdown
Metabolism
Liver: CYP2C9, 2C19, 2C8, 2C18, 1A2 and 3A4 1
- half-lifehalf gone
Elimination half-life
7 days (active half-life is 20-60 hours) 1
- exitleaves the body
Excretion
Kidney (92%) 1
Source
- Wikipedia, Warfarin, drug infobox (revision 1368670593), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.
Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.