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Vismodegib

What the body does with Vismodegib, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

VismodegibtakenExitFecal (82%), Urinary (4.4%)

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    31.8% 1

  2. hoursbreakdown

    Metabolism

    <2% metabolised by CYP2C9, CYP3A4, CYP3A5 1

  3. half-lifehalf gone

    Elimination half-life

    4 days (continuous use); 12 days (single dose) 1

  4. exitleaves the body

    Excretion

    Fecal (82%), Urinary (4.4%) 1

Source

  1. Wikipedia, Vismodegib, drug infobox (revision 1370312368), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.