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Midodrine

What the body does with Midodrine, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

MidodrinetakenDesglymidodrinemetabolite

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    ≤1 hour 1

  2. doseabsorbed

    Bioavailability

    93% (as desglymidodrine) 1

  3. hoursbreakdown

    Metabolism

    Deglycination 1

  4. hoursmade from it

    Metabolites

    Desglymidodrine 1

  5. half-lifehalf gone

    Elimination half-life

    Midodrine: 0.5 hours; Desglymidodrine: 2–4 hours 1

  6. durationeffects

    Duration of action

    2–6 hours 1

Source

  1. Wikipedia, Midodrine, drug infobox (revision 1373403734), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.