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Erlotinib

What the body does with Erlotinib, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

ErlotinibtakenExit>98% as metabolites, of which >90% via f

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    59% 1

  2. hoursbreakdown

    Metabolism

    Liver (mainly CYP3A4, less CYP1A2) 1

  3. half-lifehalf gone

    Elimination half-life

    36.2 hrs (median) 1

  4. exitleaves the body

    Excretion

    >98% as metabolites, of which >90% via feces, 9% via urine 1

Source

  1. Wikipedia, Erlotinib, drug infobox (revision 1364243315), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.