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Trimetazidine

What the body does with Trimetazidine, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

TrimetazidinetakenExitmainly renal (unchanged), exposure is in

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. doseabsorbed

    Bioavailability

    completely absorbed at around 5 hours, steady state is reached by 60th hour 1

  2. hoursbreakdown

    Metabolism

    minimal 1

  3. half-lifehalf gone

    Elimination half-life

    7 to 12 hours 1

  4. exitleaves the body

    Excretion

    mainly renal (unchanged), exposure is increased in renal impairment – on average by four-fold in subjects with severe renal impairment (CrCl <30 ml/min) 1

Source

  1. Wikipedia, Trimetazidine, drug infobox (revision 1370866766), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.