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β-Hydroxy β-methylbutyric acid

What the body does with β-Hydroxy β-methylbutyric acid, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

β-Hydroxy β-methylbutyric acidtakenExitRenal (10–40% excreted)

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    HMB-FA: 30–60 minutes; HMB-Ca: 1–2 hours 1

  2. hoursmade from it

    Metabolites

    HMB-CoA, HMG-CoA, mevalonate, cholesterol, acetyl-CoA, acetoacetate, β-hydroxybutyrate 1

  3. half-lifehalf gone

    Elimination half-life

    HMB-FA: 3 hours; HMB-Ca: 2.5 hours 1

  4. exitleaves the body

    Excretion

    Renal (10–40% excreted) 1

Source

  1. Wikipedia, Β-Hydroxy β-methylbutyric acid, drug infobox (revision 1369029857), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.