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Zolpidem

What the body does with Zolpidem, from the dose to the exit, as its Wikipedia drug infobox records it.

Quoted from the Wikipedia infobox, not yet written up by hand. The order is the usual order of events, not a measured schedule.

ZolpidemtakenExitKidney (56%); fecal (34%)

The clock, on a log scale

Each bar runs from the dose to about five half-lives, roughly when 97% of that molecule has been converted or cleared. The scale is logarithmic so minutes and days fit on one line.

  1. 0 → onsetdose

    Onset

    15 minutes (oral spray); 30 minutes (oral tablets) 1

  2. doseabsorbed

    Bioavailability

    70% (by mouth) 1

  3. hoursbreakdown

    Metabolism

    Liver through CYP3A4 (~60%), CYP2C9 (~20%), and CYP1A2 (~14%) 1

  4. hoursmade from it

    Metabolites

    (ZCA) zolpidem 6-carboxylic acid; (ZPCA) zolpidem phenyl-4-carboxylic acid 1

  5. half-lifehalf gone

    Elimination half-life

    2–3 hours 1

  6. durationeffects

    Duration of action

    3–6 hours (extended release) (duration & elimination varies by gender & age) 1

  7. exitleaves the body

    Excretion

    Kidney (56%); fecal (34%) 1

Source

  1. Wikipedia, Zolpidem, drug infobox (revision 1378287641), CC BY-SA 4.0. Values quoted as they appear, with wiki markup removed.

Half-lives vary between people, doses and routes. This page explains what the body does with a drug. It is not dosing advice.