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Sedative

Original Wikipedia articleen.wikipedia.org/wiki/Sedative revision used (24 October 2026)

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Overview

A sedative or tranquilizer or tranquilliser is a substance that induces sedation by reducing irritability or excitement.[1] PW

A general anaesthetic, or sedative, is often defined as a compound that induces a loss of consciousness in humans or loss of righting reflex in animals. Clinical definitions are also extended to include an induced coma that causes lack of awareness to painful stimuli, sufficient to facilitate surgical applications in clinical and veterinary practice. General anaesthetics do not act as analgesics. General anaesthetics are a structurally diverse group of compounds whose mechanisms encompass multiple biological targets involved in the control of neuronal pathways. The precise workings are the subject of some debate and ongoing research.[2] WP⚠ The source has a footnote here that is not shown.

General anesthetics elicit a state of general anesthesia. It remains somewhat controversial regarding how this state should be defined. General anesthetics, however, typically elicit several key reversible effects: immobility, analgesia, amnesia, unconsciousness, and reduced autonomic responsiveness to noxious stimuli.[3][4][5] WP

Drugs in this class on intoxicant.wiki

Every page on this site that a cited source puts in this class: 20 pages. A drug is listed when PsychonautWiki's "Sedative" page, revision 163431 lists it, or when its own PsychonautWiki, TripSit or Wikipedia entry names this class. Each name opens our page for that drug; long chemical names are shown by a shorter name the drug is also known by (hover for the full name).

Tags show who puts each drug in this class (hover for the exact wording): PW list = listed on PsychonautWiki's page for this class; PW = the drug's PsychonautWiki entry; TS = the drug's TripSit entry (drug category); WP = the drug infobox of the drug's Wikipedia article. These are classifications only, not dosage guidance.

References

  1. Other Johns Hopkins Colon Cancer Center - Glossary S
  2. Journal / agency Franks, Nicholas P. General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal. Nature Reviews Neuroscience. May 2008. doi:10.1038/nrn2372 · PMID 18425091
  3. Journal / agency Brown, Emery N.; Purdon, Patrick L.; Van Dort, Christa J. General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis. Annual Review of Neuroscience. 2011-06-21. doi:10.1146/annurev-neuro-060909-153200 · PMID 21513454 · PMC3390788
  4. Other Goodman & Gilman's pharmacological basis of therapeutics. 2011
  5. Other Katzung, Bertram G.; Trevor, Anthony J. Basic and clinical pharmacology. 2014-12-23

Text and values on this page are quoted from PsychonautWiki (CC BY-SA 4.0), Wikipedia (CC BY-SA 4.0). Each value links to the exact revision it came from.