Compound

Tuinal

Also called Perdormal

Original Wikipedia articleen.wikipedia.org/wiki/Tuinal revision used (24 October 2026)

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Common dose · Oral75–150 mg. TS

Dosage

Oral

Source	Threshold	Light	Common	Strong	Heavy
TripSit	–	25–75 mg TS	75–150 mg. TS	150–300 mg. TS	–

TripSit dose text

TripSit's factsheet also states its doses as text.

Oral Light: 25-75mg Common: 75-150mg. Strong: 150-300mg. TS

What dose are you on? (self-reported, unverified)

Read this first. These numbers come from anonymous visitors typing in a box. Nobody checks them. People misjudge, mistype, troll, or take untested products of unknown strength. They are not a dose guide and never override the sourced table above. They exist only so the sourced ranges can be compared with what people say they take. If you are deciding what to take, use the sourced table, start low, and read the risks section.

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Duration

TripSit factsheet

Onset: 10-45 minutes TS
Duration: 5-12 hours TS
Aftereffects: 1-8 hours TS

Mixing

For best safety practice, don't mix this drug with other depressants.

Why: respiratory depression. PsychonautWiki says:

“Respiratory depression (also known as hypoventilation) can be described as a reduced urge to breathe that can be fatal depending on its intensity.” (PsychonautWiki, Respiratory depression, revision 150612)
“... otherwise safe dosages of these compounds can become fatal when combined with even small amounts of other classes of depressant. For example, benzodiazepines combined with opioids are an extremely common cause of fatal respiratory depression. It is therefore strongly discouraged to combine these depressants at any dosage range.” (PsychonautWiki, Respiratory depression, revision 150612)
“The most common cause of substance-related deaths is the combination of depressants (such as opiates, benzodiazepines, or alcohol) with other depressants.” (PsychonautWiki, Responsible drug use, revision 168206)
“This combination potentiates the muscle relaxation, amnesia, sedation, and respiratory depression caused by one another. At higher doses, it can lead to a sudden, unexpected loss of consciousness along with a dangerous amount of depressed respiration.” (PsychonautWiki, dangerous interactions table, "Depressants" row, revision 156847)

Quotes from PsychonautWiki, CC BY-SA 4.0.

Acute combinations: what happens when these are taken close together. Entries backed by a medical journal or agency are listed first.

Backed by medical journals

Awaiting sourcePeer-reviewed reports on acute combinations, from PubMed and the journals the harm reduction sites cite.

Risks and toxicity

TripSit factsheet

Avoid: All other CNS depressants. TS

Testing

Awaiting sourceReagent reactions and test kit guidance from a harm reduction testing service.

Effects

Awaiting sourceSubjective and physical effects from PsychonautWiki or TripSit.

Overview

Brand name of a combination drug of two barbiturate salts (Secobarbital/Amobarbital) in equal amounts. It was introduced in the late 1940's. TS

Tuinal was the brand name of a discontinued combination drug composed of two barbiturate sodium salts (secobarbital and amobarbital) in equal proportions. WP

Tuinal was introduced as a sedative–hypnotic (sleeping pill) medication in the late 1940s by Eli Lilly. It was also used in obstetrics for childbirth. It was produced in brightly colored half-reddish orange and half-turquoise blue gelatin capsule form (bullet-shaped Pulvules) for oral administration. Individual capsules contained 50 mg, 100 mg, or 200 mg of barbiturate salts. The combination of a short-acting barbiturate, secobarbital, with an intermediate-acting barbiturate, amobarbital, aimed to provide "a rapid yet prolonged hypnotic action".[1][2][3] WP

Eli Lilly has discontinued the manufacture of Tuinal in the United States due to the diminishing use of barbiturates (largely replaced by the benzodiazepine family of drugs) in outpatient treatment, and its widespread abuse. Currently, Valleant Labs markets secobarbital capsules only. Flynn Pharma of Ireland no longer manufactures Tuinal, Seconal (secobarbital), or Amytal (amobarbital). Amytal has been discontinued, though injectable forms of amobarbital sodium remain.[4] WP⚠ Wikipedia itself has flagged this text: citation needed.

History

Awaiting sourceHistory and culture from Wikipedia or PsychonautWiki, with their citations.

Legal status

Society and culture

The drug was featured in "Psycho Therapy," a song by the musical band Ramones, who stated "I like takin' Tuinal/It keeps me edgy and mean/I'm a teenage schizoid/I'm a teenage dope fiend." WP⚠ Wikipedia itself has flagged this text: citation needed.

It is also mentioned in "Lost Johnny" a song by the band Hawkwind in the last verse, "And we're all taking Tuinal/to murder our young dreams." WP⚠ Wikipedia itself has flagged this text: citation needed.

Most famously, Tuinal is mentioned by Shane MacGowan in the song "Old Main Drag" by The Pogues. WP⚠ Wikipedia itself has flagged this text: citation needed.

Tuinal is mentioned in Fight Club by Chuck Palahniuk: "I just wanted to sleep. I wanted little blue Amytal Sodium capsules, 200-milligram-sized. I wanted red-and-blue Tuinal bullet capsules, lipstick-red Seconal." WP⚠ Wikipedia itself has flagged this text: citation needed.

Tuinal describes some people in the song "New Sensations" by Lou Reed. WP

Tuinal is mentioned in the song "Doctor Rockter" by the band W.A.S.P., in which the narrator details his rampant drug abuse and dealer. "Cocaine, codeine, 714/a Tuinal blindfold, just what I need." WP⚠ Wikipedia itself has flagged this text: citation needed.

Pharmacology

Awaiting sourcePharmacology from Wikipedia and the journal papers it cites.

Chemistry

Formula: C23H34N4Na2O6 PC
CAS number: 8065-05-2 PC
Molar mass (g/mol): 508.5 PC
IUPAC name (computed by PubChem): disodium;2,6-dioxo-5-pentan-2-yl-5-prop-2-enylpyrimidin-4-olate;5-ethyl-5-(3-methylbutyl)-2,6-dioxopyrimidin-4-olate PC
SMILES: CCCC(C)C1(C(=O)NC(=O)N=C1[O-])CC=C.CCC1(C(=O)NC(=O)N=C1[O-])CCC(C)C.[Na+].[Na+] PC
InChIKey: HQBIOVWPIHUNKN-UHFFFAOYSA-L PC
PubChem CID: 3080650

User reports

Erowid erowid.org

Listings

Awaiting sourceExperience Vault listing and report categories.

Bluelight bluelight.org

Listings

Awaiting sourceTrip report threads and this substance's discussion forum.

Reddit reddit.com

Listings

Awaiting sourceTrip report posts and the relevant subreddits.

Pop culture

No references added yet.

Add a reference

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References

Journal / agency Waters AB. Pethidine In Labour. The British Medical Journal. 1947. doi:10.1136/bmj.2.4514.71-b · PMID 20344014 · PMC2055200
Journal / agency Front Matter. The British Medical Journal. 1948
Journal / agency Front Matter. The American Journal of Nursing. 1947
Other Mitchell M, Willingham EJ, Atkins WA. The Gale Encyclopedia of Mental Health. 2012

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), TripSit factsheets, PubChem (public domain). Each value links to the exact revision it came from.