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Substance

Didesmethylcitalopram

Also called Didemethylcitalopram, Rac-didesmethylcitalopram

Original Wikipedia articleen.wikipedia.org/wiki/Didesmethylcitalopram revision used (24 October 2026)

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Part of the metabolic pathway of Citalopram and Escitalopram. See the timeline on the metabolic highway.

Overview

Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic). Didesmethylescitalopram is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.[1] WP

Chemistry

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Harm reduction information

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Sources

  1. Journal / agency Rop PP, Durand A, Viala A, Jørgensen A. Simultaneous determination of citalopram, monodesmethylcitalopram and didesmethylcitalopram in plasma by high-performance liquid chromatography after column extraction. Journal of Chromatography. April 1990. doi:10.1016/s0378-4347(00)82105-2 · PMID 2365786

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