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Compound

Vilanterol

Original Wikipedia articleen.wikipedia.org/wiki/Vilanterol revision used (24 October 2026)

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Overview

Vilanterol is an ultra-long-acting β₂-adrenoceptor agonist which was approved in May 2013 in combination with fluticasone furoate for sale as Breo Ellipta by GlaxoSmithKline for the treatment of chronic obstructive pulmonary disease (COPD). The combination is also approved for the treatment of asthma in Canada, Europe, Japan and New Zealand.[1–4] WP

Vilanterol is available in following combinations: WP

with inhaled corticosteroid fluticasone furoate—fluticasone furoate/vilanterol (trade names Breo Ellipta (U.S., NZ), Relvar Ellipta (EU, RU, JPN)) WP

with muscarinic antagonist umeclidinium bromide—umeclidinium bromide/vilanterol (trade name Anoro Ellipta) WP

with inhaled corticosteroid fluticasone furoate and muscarinic antagonist umeclidinium bromide—fluticasone furoate/umeclidinium bromide/vilanterol (trade name Trelegy Ellipta) WP

Chemistry

Formula
C24H33Cl2NO5 PC
CAS number
503068-34-6 PC
Molar mass (g/mol)
486.4 PC
IUPAC name (computed by PubChem)
4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol PC
SMILES
C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNC[C@@H](C2=CC(=C(C=C2)O)CO)O)Cl PC
InChIKey
DAFYYTQWSAWIGS-DEOSSOPVSA-N PC
PubChem CID
10184665

Harm reduction information

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Sources

  1. Journal / agency FDA approves Breo Ellipta to treat chronic obstructive pulmonary disease
  2. Journal / agency McKeage K. Fluticasone furoate/vilanterol: a review of its use in chronic obstructive pulmonary disease. Drugs. September 2014. doi:10.1007/s40265-014-0269-6 · PMID 25074268
  3. Journal / agency Syed YY. Fluticasone furoate/vilanterol: a review of its use in patients with asthma. Drugs. March 2015. doi:10.1007/s40265-015-0354-5 · PMID 25648266
  4. Other Zealand (www.bka.co.nz), Site designed and developed by bka interactive ltd, Auckland, New. Fluticasone and vilanterol | Health Navigator NZ. 22 June 2019

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.