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Compound

Tybamate

Also called Tibamato, Tybatran, Solacen

Original Wikipedia articleen.wikipedia.org/wiki/Tybamate revision used (24 October 2026)

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Part of the metabolic pathway of Tybamate. See the timeline on the metabolic highway.

Overview

Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker.[1][2] WP

As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions.[3] WP

Chemistry

Formula
C13H26N2O4 PC
CAS number
4268-36-4 PC
Molar mass (g/mol)
274.36 PC
IUPAC name (computed by PubChem)
[2-(carbamoyloxymethyl)-2-methylpentyl] N-butylcarbamate PC
SMILES
CCCCNC(=O)OCC(C)(CCC)COC(=O)N PC
InChIKey
PRBORDFJHHAISJ-UHFFFAOYSA-N PC
PubChem CID
20266

Harm reduction information

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Sources

  1. Other Index Nominum 2000: International Drug Directory. January 2000
  2. Journal / agency Segelman FH, Kelton E, Terzi RM, Kucharczyk N, Sofia RD. The comparative potency of phenobarbital and five 1,3-propanediol dicarbamates for hepatic cytochrome P450 induction in rats. Research Communications in Chemical Pathology and Pharmacology. June 1985. PMID 4023427
  3. Other American Medical Association Dept of Drugs. AMA Drug Evaluations. 1977

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.