Tilorone
Also called Bis-DEAE-fluorenone, 2,7-Bis-DEAE-fluorenone, DEAE-F
Part of the metabolic pathway of Tilorone. See the timeline on the metabolic highway.
Overview
Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer. It is used as an antiviral drug in some countries which do not require double-blind placebo-controlled studies, including Russia. It is effective against Ebola virus in mice. It shows activity against Eastern equine encephalitis and related viruses.[1]
Pharmacology
Pharmacology
Chemistry
- Formula
- C25H34N2O3 PC
- CAS number
- 27591-97-5 PC
- Molar mass (g/mol)
- 410.5 PC
- IUPAC name (computed by PubChem)
- 2,
7- PCbis[2- (diethylamino) ethoxy] fluoren- 9- one - SMILES
- CCN(CC)
CCOC1=CC2=C(C=C1) PCC3=C(C2=O) C=C(C=C3) OCCN(CC) CC - InChIKey
- MPMFCABZENCRHV-
UHFFFAOYSA- PCN - PubChem CID
- 5475
- IUPAC name
- 2,
7- WPBis(2- diethylaminoethoxy) fluoren- 9- one
Harm reduction information
No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.
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Sources
- Journal / agency Stringfellow DA, Glasgow LA. Tilorone hydrochloride: an oral interferon-inducing agent. Antimicrobial Agents and Chemotherapy. August 1972. doi:10.1128/aac.2.2.73 · PMID 4670490 · PMC444270
- Journal / agency Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB. Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection. Antimicrobial Agents and Chemotherapy. February 2018. doi:10.1128/AAC.01711-17 · PMID 29133569 · PMC5786809
- Journal / agency Ogorek TJ, Golden JE. Advances in the Development of Small Molecule Antivirals against Equine Encephalitic Viruses. Viruses. February 2023. doi:10.3390/v15020413 · PMID 36851628 · PMC9958955
Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.