intoxicant.wiki2catechol4school
Compound

Thiorphan

Also called Tiorphan, S-Thiorphan

Original Wikipedia articleen.wikipedia.org/wiki/Thiorphan revision used (24 October 2026)

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Part of the metabolic pathway of Racecadotril. See the timeline on the metabolic highway.

Overview

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan). It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1][2] WP

Chemistry

Formula
C12H15NO3S PC
CAS number
76721-89-6 PC
Molar mass (g/mol)
253.32 PC
IUPAC name (computed by PubChem)
2-[(2-benzyl-3-sulfanylpropanoyl)amino]acetic acid PC
SMILES
C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O PC
InChIKey
LJJKNPQAGWVLDQ-UHFFFAOYSA-N PC
PubChem CID
3132

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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Sources

  1. Journal / agency Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F. In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF. European Journal of Pharmacology. June 1986. doi:10.1016/0014-2999(86)90094-4 · PMID 3015640
  2. Journal / agency Matheson AJ, Noble S. Racecadotril. Drugs. April 2000. doi:10.2165/00003495-200059040-00010 · PMID 10804038

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.