intoxicant.wiki2catechol4school
Compound

Tenatoprazole

Also called Protop, Ulsacare, Benatoprazole

Original Wikipedia articleen.wikipedia.org/wiki/Tenatoprazole revision used (24 October 2026)

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Part of the metabolic pathway of Tenatoprazole. See the timeline on the metabolic highway.

Enzymes that break it down: CYP2C19. Wikipedia’s drug infobox says: “Hepatic (CYP2C19-mediated)” (revision 1332224692).

Overview

Tenatoprazole is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer as far back as 2003. The compound was invented by Mitsubishi Tanabe Pharma and was licensed to Negma Laboratories (part of Wockhardt as of 2007).[1][2][3] WP

Mitsubishi reported that tenatoprazole was still in Phase I clinical trials in 2007 and again in 2012.[3][4] WP

Tenatoprazole has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump inhibitors, and has a half-life about seven times longer than other PPIs.[5] WP

Chemistry

Formula
C16H18N4O3S PC
CAS number
113712-98-4 PC
Molar mass (g/mol)
346.4 PC
IUPAC name (computed by PubChem)
5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine PC
SMILES
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC PC
InChIKey
ZBFDAUIVDSSISP-UHFFFAOYSA-N PC
PubChem CID
636411

Harm reduction information

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Sources

  1. Other Gastrointestinal Disease Update. March 2003
  2. Other Investors unwilling to forgive Wockhardt, promoter for failings. 3 March 2011
  3. Other State of New Product Development. 8 May 2012
  4. Other FY2007 Interim Financial Results
  5. Journal / agency Li H, Meng L, Liu F, Wei JF, Wang YQ. H+/K+-ATPase inhibitors: a patent review. Expert Opinion on Therapeutic Patents. January 2013. doi:10.1517/13543776.2013.741121 · PMID 23205582

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.