intoxicant.wiki2catechol4school
Compound

RE-109

Also called 5-[[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl]oxy]-5-oxopentanoic acid

Original Wikipedia articleen.wikipedia.org/wiki/RE-109 revision used (24 October 2026)

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Part of the metabolic pathway of RE-109. See the timeline on the metabolic highway.

Overview

O-Glutarylpsilocin (developmental code name RE109), also known as 4-glutaryloxy-N,N-dimethyltryptamine (4-HO-DMT O-glutarate or 4-GO-DMT) is a serotonergic psychedelic of the tryptamine family. It acts as a prodrug of psilocin (4-HO-DMT) similarly to other psilocin prodrugs like 4-AcO-DMT, 4-PrO-DMT, and psilocybin (4-PO-DMT). The drug is cleaved into psilocin by non-specific esterases. O-Glutarylpsilocin was first described in the scientific literature in 2024. It has been patented by Reunion Neuroscience. A related drug, luvesilocin (RE-104, FT-104; 4-GO-DiPT), a prodrug of 4-HO-DiPT, is being developed for potential medical use.[1][2] WP

Chemistry

Formula
C17H22N2O4 PC
Molar mass (g/mol)
318.4 PC
IUPAC name (computed by PubChem)
5-[[3-[2-(dimethylamino)ethyl]-1H-indol-4-yl]oxy]-5-oxopentanoic acid PC
SMILES
CN(C)CCC1=CNC2=C1C(=CC=C2)OC(=O)CCCC(=O)O PC
InChIKey
GIDBNBKWKCJUNZ-UHFFFAOYSA-N PC
PubChem CID
162510633

Harm reduction information

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Sources

  1. Journal / agency Bryson N, Alexander R, Asnis-Alibozek A, Ehlers MD. RE104: Synthesis and Activity of a Novel Serotonergic Psychedelic Prodrug of 4-Hydroxy-N,N-diisopropyltryptamine. ACS Chem Neurosci. June 2024. doi:10.1021/acschemneuro.4c00058 · PMID 38758589 · PMC11191588
  2. Other Improved pharmacokinetics of tryptamine prodrugs. 4 January 2024

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.