intoxicant.wiki2catechol4school
Compound

Proxibarbital

Also called Hydroxydial, Ipronal, Axeen

Original Wikipedia articleen.wikipedia.org/wiki/Proxibarbital revision used (24 October 2026)

Why a "revision used" link? Anyone can edit Wikipedia at any time, so the article you open today may not say what it said when we read it. This link opens the exact version we read on 24 October 2026, frozen as it was. It is the only way to check that every quote on this page matches its source word for word. Newer versions may correct or change things. When we re-check this page against a newer version, the edit log records it. How we cite

Overview

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956 in Poland by Bogusław Bobrański. It has anti-anxiety and sedative properties and is, in contrast to most barbiturates, almost without hypnotic action. It was used as a sedative and anti-anxiety drug. It was also used in the treatment of migraine headaches in a similar manner to butalbital. It was a prescription drug available in Poland from the 1950s to the 1990s under trade name Ipronal.[1][2] WP

Valofane isomerizes to proxibarbal in vivo.[3] WP

Chemistry

Formula
C10H14N2O4 PC
CAS number
2537-29-3 PC
Molar mass (g/mol)
226.23 PC
IUPAC name (computed by PubChem)
5-(2-hydroxypropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione PC
SMILES
CC(CC1(C(=O)NC(=O)NC1=O)CC=C)O PC
InChIKey
VNLMRPAWAMPLNZ-UHFFFAOYSA-N PC
PubChem CID
17336
IUPAC name
(RS)-5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1H,3H,5H)-trione WP

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

Awaiting sourceChecked against PsychonautWiki and TripSit as each pull runs. This box is replaced as soon as a source has data.

User reports

Erowid erowid.org

Listings
Awaiting sourceExperience Vault listing and report categories.
Top stories
Awaiting sourceShort summaries of the most-read reports, each linked, saying only what the report says.

Bluelight bluelight.org

Listings
Awaiting sourceTrip report threads and this substance's discussion forum.
Top stories
Awaiting sourceShort summaries of the most-read reports, each linked, saying only what the report says.

Reddit reddit.com

Listings
Awaiting sourceTrip report posts and the relevant subreddits.
Top stories
Awaiting sourceShort summaries of the most-read reports, each linked, saying only what the report says.

Pop culture

No references added yet.

Add a reference

Registered users can add songs, films, books, shows, games and art about this substance. Link a source that names the substance, such as the work's Wikipedia article, a review or an interview, not only the work itself. Entries are voted on and moderated like every other value on this page.

Opens when accounts launch.

Sources

  1. Other Zajdel P, Kulig K, Zejc A. Chemia leków, podręcznik dla studentów farmacji i farmaceutów. 2008
  2. Journal / agency Sulman FG, Pfeifer Y, Tal E. Migraine therapy by enzyme induction with proxibarbital. Therapie der Gegenwart. December 1976. PMID 14412
  3. Journal / agency Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981. doi:10.1007/BF03189485 · PMID 6118275

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.