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Compound

Pinoxepin

Original Wikipedia articleen.wikipedia.org/wiki/Pinoxepin revision used (24 October 2026)

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Overview

Pinoxepin (INN (International Nonproprietary Name); developmental code name P-5227; pinoxepin hydrochloride (USAN (United States Adopted Name))) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed. It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine. The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.[1–5] WP

Chemistry

Formula
C23H27ClN2O2 PC
CAS number
14008-66-3 PC
Molar mass (g/mol)
398.9 PC
IUPAC name (computed by PubChem)
2-[4-[(3Z)-3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol PC
SMILES
C1CN(CCN1CC/C=C\2/C3=CC=CC=C3COC4=C2C=C(C=C4)Cl)CCO PC
InChIKey
RAAHIUIRJUOMAU-MPUCSWFWSA-N PC
PubChem CID
6436541

Harm reduction information

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Sources

  1. Other Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014
  2. Other Annual Reports in Medicinal Chemistry. 1 January 1967
  3. Other Gordon M. Psychopharmacological Agents. 2 December 2012
  4. Other Iversen L. Handbook of Psychopharmacology: Volume 10: Neoroleptics and Schizophrenia. 6 December 2012
  5. Other Lajtha A. Alterations of Metabolites in the Nervous System. 11 November 2013

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.