Compound

Ornidazole

Also called Tiberal, Madelen, Ornidal

Original Wikipedia articleen.wikipedia.org/wiki/Ornidazole revision used (24 October 2026)

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Part of the metabolic pathway of Ornidazole. See the timeline on the metabolic highway.

Overview

Ornidazole is an antibiotic used to treat protozoan infections. A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin. Ornidazole is nothing but chloro-secnidazole.[1][2] WP

Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; however there are concerns of lower relative efficacy.[1][3] WP

It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities. has also been investigated for use in Crohn's disease after bowel resection.[4][5] WP

Chemistry

Formula: C7H10ClN3O3 PC
CAS number: 16773-42-5 PC
Molar mass (g/mol): 219.62 PC
IUPAC name (computed by PubChem): 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol PC
SMILES: CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-] PC
InChIKey: IPWKIXLWTCNBKN-UHFFFAOYSA-N PC
PubChem CID: 28061
IUPAC name: 1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol WP

Harm reduction information

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Sources

Journal / agency Kuhlmann FM, Fleckenstein JM. Infectious Diseases. 2017-01-01. doi:10.1016/B978-0-7020-6285-8.00157-X
Journal / agency Sharma S, Anand N. Pharmacochemistry Library. January 1997. doi:10.1016/S0165-7208(97)80039-6
Other Nagel JL, Aronoff DM. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. January 2015
Other Wilcox MH. Infectious Diseases. January 2017
Journal / agency Rutgeerts P, Van Assche G, Vermeire S, D'Haens G, Baert F, Noman M, Aerden I, De Hertogh G, Geboes K, Hiele M, D'Hoore A, Penninckx F. Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology. April 2005. doi:10.1053/j.gastro.2005.01.010 · PMID 15825069

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.