Compound

Orciprenaline

Also called Metaproterenol, Metaprel, Alotec

Original Wikipedia articleen.wikipedia.org/wiki/Orciprenaline revision used (24 October 2026)

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Part of the metabolic pathway of Orciprenaline. See the timeline on the metabolic highway.

Overview

Orciprenaline, also known as metaproterenol, is a bronchodilator used in the treatment of asthma. Orciprenaline is a moderately selective β₂ adrenergic receptor agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on α adrenergic receptors. The pharmacologic effects of β adrenergic agonist drugs, such as orciprenaline, are at least in part attributable to stimulation through β adrenergic receptors of intracellular adenylyl cyclase, the enzyme which catalyzes the conversion of ATP to cAMP. Increased cAMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from many cells, especially from mast cells.[1][2] WP

Risks and side effects

Adverse effects

More common side effects of metaproterenol include tachycardia and nervousness. Additional side effects with >1% incidence include headache, nausea, and tremor. A non-exhaustive list of rare side effects includes other cardiovascular symptoms, dizziness, fatigue, etc.[3][4] WP

Chemistry

Formula: C11H17NO3 PC
CAS number: 586-06-1 PC
Molar mass (g/mol): 211.26 PC
IUPAC name (computed by PubChem): 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol PC
SMILES: CC(C)NCC(C1=CC(=CC(=C1)O)O)O PC
InChIKey: LMOINURANNBYCM-UHFFFAOYSA-N PC
PubChem CID: 4086

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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Pop culture

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Sources

Journal / agency Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. DrugBank 3.0: a comprehensive resource for omics research on drugs. Nucleic Acids Res. 2011. doi:10.1093/nar/gkq1126 · PMID 21059682 · PMC3013709
Journal / agency Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M. DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008. doi:10.1093/nar/gkm958 · PMID 18048412 · PMC2238889
Journal / agency Metaproterenol Sulfate Syrup, USP
Other Metaproterenol Side Effects: Common, Severe, Long Term

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.