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Compound

Normustine

Original Wikipedia articleen.wikipedia.org/wiki/Normustine revision used (24 October 2026)

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Part of the metabolic pathway of Estramustine phosphate. See the timeline on the metabolic highway.

Overview

Normustine, also known as bis(2-chloroethyl)carbamic acid, is a nitrogen mustard and alkylating antineoplastic agent (i.e., chemotherapy agent). It is a metabolite of a number of antineoplastic agents that have been developed for the treatment of tumors, including estramustine phosphate, alestramustine, cytestrol acetate, and ICI-85966 (stilbostat), but only the former of which has actually been marketed.[1][2][3] WP

Chemistry

Formula
C5H9Cl2NO2 PC
CAS number
78619-95-1 PC
Molar mass (g/mol)
186.03 PC
IUPAC name (computed by PubChem)
bis(2-chloroethyl)carbamic acid PC
SMILES
C(CCl)N(CCCl)C(=O)O PC
InChIKey
TTYAKTJQJVVKED-UHFFFAOYSA-N PC
PubChem CID
18377863
IUPAC name
Bis(2-chloroethyl)carbamic acid WP

Harm reduction information

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Sources

  1. Other Brunton L, Chabner B, Knollman B. Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition. 14 January 2011
  2. Other Fox BW, Fox M. Antitumor Drug Resistance. 6 December 2012
  3. Other Decker M. Design of Hybrid Molecules for Drug Development. 5 April 2017

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.