N-Methylbisfluoromodafinil
Also called Dehydroxyfluorafinil, Modafiendz
Dosage
Oral bands as drawn from PsychonautWiki's ranges below. The table is the source of truth.
When sources disagree, both rows are shown as published. Nothing is averaged or merged.
Oral
| Source | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| PsychonautWiki | 25 mg PW | 50–100 mg PW | 100–150 mg PW | 150–200 mg PW | 200 mg+ PW |
| TripSit | – | 50–100 mg TS | 100–150 mg TS | 150–200 mg+ TS | – |
TripSit dose text
TripSit's factsheet also states its doses as text.
Threshold 25-50mg Light: 50-100mg Common: 100-150mg Strong: 150-200mg+ TS
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Duration
| Route · source | Onset | Come-up | Peak | Offset | Total | After-effects |
|---|---|---|---|---|---|---|
| Oral · PsychonautWiki | – | – | – | – | 5–8 hours PW | – |
TripSit factsheet
Mixing
For best safety practice, don't mix this drug with other stimulants.
Why: vasoconstriction, heart rate and blood pressure. PsychonautWiki says:
- “... may be dangerous to combine with other stimulants ... as they can increase one's heart rate and blood pressure to dangerous levels.” (PsychonautWiki, dangerous interactions table, "Stimulants" row, revision 148925)
- “Vasoconstriction can be described as a narrowing of the veins and blood vessels which results from a contraction of their muscular wall.” (PsychonautWiki, Vasoconstriction, revision 170337)
- “... it can also occur under the influence of traditional stimulants such as methamphetamine, caffeine, and MDMA.” (PsychonautWiki, Vasoconstriction, revision 170337)
- “Increased blood pressure is most commonly induced under the influence of heavy dosages of vasoconstricting compounds, such as traditional stimulants and stimulating psychedelics.” (PsychonautWiki, Increased blood pressure, revision 152273)
Quotes from PsychonautWiki, CC BY-SA 4.0.
Acute combinations: what happens when these are taken close together. Entries backed by a medical journal or agency are listed first.
Backed by medical journals
Other documented combinations
- MDMA - The neurotoxic effects of MDMA may be increased when combined with other stimulants. PW⚠ PsychonautWiki lists this combination without a danger rating.
- Cocaine - This combination may increase strain on the heart. PW⚠ PsychonautWiki lists this combination without a danger rating.
PsychonautWiki also lists dangerous combinations shared across a whole group (MAOIs, stimulants) in a table this page does not copy. Read that list on PsychonautWiki.
Risks and toxicity
The toxicity and long-term health effects of recreational N-methylbisfluoromodafinil use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because N-methylbisfluoromodafinil has very little history of human usage. Anecdotal evidence from people who have tried N-methylbisfluoromodafinil within the community suggests that there do not seem to be any negative health effects attributed to simply trying this substance at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance. PW
Tolerance and addiction potential
The chronic use of N-methylbisfluoromodafinil can be considered as mildly addictive with a low potential for abuse and it does not seem to be capable of causing psychological dependence among certain users due to its lack of euphoria or recreational effects. If addiction has developed, cravings and withdrawal effects may occur if a person suddenly stops their usage. PW
Tolerance to many of the effects of N-methylbisfluoromodafinil develops with prolonged and repeated use. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about 3 - 7 days for the tolerance to be reduced to half and 1 - 2 weeks to be back at baseline (in the absence of further consumption). N-methylbisfluoromodafinil presents cross-tolerance with all modafanil analogs, meaning that after the consumption of N-methylbisfluoromodafinil all modafinil analogs will have a reduced effect. PW⚠ PsychonautWiki itself has flagged this text: citation needed.
Testing
Effects
Overview
N-Methyl-4,4'-difluoro-modafinil (also known as N-Methylbisfluoromodafinil, Dehydroxyfluorafinil, and Modafiendz) is an obscure nootropic of the benzhydryl class with no history of research. Although it is closely related on a structural level to adrafinil and modafinil, neither a pharmacological nor a safety-profile similarity should be assumed.[1] PW
Nootropic of the benzhydryl class. Closely related to Adrafinil and Modafinil. Was branded as "Modafiendz" through some research chemical vendors. TS
History
Legal status
- N-methylbisfluoromodafinil is currently a gray area compound within most (if not all) parts of the world. This means that it is not known to be specifically illegal within any country, but people may still be charged for its possession under certain circumstances such as under analog laws and with intent to sell or consume. PW
- United Kingdom - It is illegal to produce, supply, or import this substance under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[2] PW
Pharmacology
Chemistry
User reports
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References
Text and values on this page are quoted from PsychonautWiki (CC BY-SA 4.0), TripSit factsheets. Each value links to the exact revision it came from.