Depressant

Mephenaqualone

Original Wikipedia articleNot linked yet. It gets linked once the exact article is confirmed.

Common dose · Oral1.5–2.5 mg PW

Onset30–40 minutes PW

Total15–20 hours PW

After-effects6–12 hours PW

Dosage

Threshold

Light

Common

Strong

Heavy

00.51.52.54mg

Oral bands as drawn from PsychonautWiki's ranges below. The table is the source of truth.

Oral

Source	Threshold	Light	Common	Strong	Heavy
PsychonautWiki	0.5 mg PW	0.5–1.5 mg PW	1.5–2.5 mg PW	2.5–4 mg PW	4 mg+ PW

What dose are you on? (self-reported, unverified)

Read this first. These numbers come from anonymous visitors typing in a box. Nobody checks them. People misjudge, mistype, troll, or take untested products of unknown strength. They are not a dose guide and never override the sourced table above. They exist only so the sourced ranges can be compared with what people say they take. If you are deciding what to take, use the sourced table, start low, and read the risks section.

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Duration

Onset

Come-up

Peak

Offset

0h4h8h12h16h

Oral, drawn at the midpoint of each PsychonautWiki range.

Route · source	Onset	Come-up	Peak	Offset	Total	After-effects
Oral · PsychonautWiki	30–40 minutes PW	5–10 minutes PW	2–4 hours PW	10–15 hours PW	15–20 hours PW	6–12 hours PW

Mixing

For best safety practice, don't mix this drug with other depressants.

Why: respiratory depression. PsychonautWiki says:

“Respiratory depression (also known as hypoventilation) can be described as a reduced urge to breathe that can be fatal depending on its intensity.” (PsychonautWiki, Respiratory depression, revision 150612)
“... otherwise safe dosages of these compounds can become fatal when combined with even small amounts of other classes of depressant. For example, benzodiazepines combined with opioids are an extremely common cause of fatal respiratory depression. It is therefore strongly discouraged to combine these depressants at any dosage range.” (PsychonautWiki, Respiratory depression, revision 150612)
“The most common cause of substance-related deaths is the combination of depressants (such as opiates, benzodiazepines, or alcohol) with other depressants.” (PsychonautWiki, Responsible drug use, revision 168206)
“This combination potentiates the muscle relaxation, amnesia, sedation, and respiratory depression caused by one another. At higher doses, it can lead to a sudden, unexpected loss of consciousness along with a dangerous amount of depressed respiration.” (PsychonautWiki, dangerous interactions table, "Depressants" row, revision 156847)

Quotes from PsychonautWiki, CC BY-SA 4.0.

Acute combinations: what happens when these are taken close together. Entries backed by a medical journal or agency are listed first.

Backed by medical journals

Awaiting sourcePeer-reviewed reports on acute combinations, from PubMed and the journals the harm reduction sites cite.

Risks and toxicity

The toxicity profile of mephenaqualone is not well-documented, but it is assumed to be similar to that of methaqualone. Overdosing on mephenaqualone can lead to severe sedation, respiratory depression, and potentially life-threatening symptoms. As with all CNS depressants, combining mephenaqualone with other depressants like alcohol or benzodiazepines significantly increases the risk of overdose and fatal respiratory depression. PW

Testing

Awaiting sourceReagent reactions and test kit guidance from a harm reduction testing service.

Effects

Awaiting sourceSubjective and physical effects from PsychonautWiki or TripSit.

Overview

Mephenaqualone is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. It is an analogue of methaqualone, sharing a similar chemical structure and pharmacological effects. PW

History

Awaiting sourceHistory and culture from Wikipedia or PsychonautWiki, with their citations.

Legal status

Germany: Mephenaqualone is currently legal, as it is classified as a designer drug and not specifically controlled under the BtMG (Narcotics Act). However, its legal status could be subject to change as more is learned about the substance and its effects. PW⚠ PsychonautWiki itself has flagged this text: citation needed.
Other countries: The legal status of mephenaqualone in other countries is largely unknown. It is not widely documented and may vary significantly depending on local laws regarding designer drugs and analogs of controlled substances. PW⚠ PsychonautWiki itself has flagged this text: citation needed.

Pharmacology

Awaiting sourcePharmacology from Wikipedia and the journal papers it cites.

Chemistry

Awaiting sourceFormula, structure and identifiers from PubChem.

User reports

Erowid erowid.org

Listings

Awaiting sourceExperience Vault listing and report categories.

Bluelight bluelight.org

Listings

Awaiting sourceTrip report threads and this substance's discussion forum.

Reddit reddit.com

Listings

Awaiting sourceTrip report posts and the relevant subreddits.

Pop culture

No references added yet.

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References

This page cites its source pages directly. None of them listed further references for the values shown.

Text and values on this page are quoted from PsychonautWiki (CC BY-SA 4.0). Each value links to the exact revision it came from.