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Substance

Alatrofloxacin

Original Wikipedia articleen.wikipedia.org/wiki/Alatrofloxacin revision used (24 October 2026)

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Part of the metabolic pathway of Alatrofloxacin. See the timeline on the metabolic highway.

Overview

Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It is a prodrug of Trovafloxacin.[1][2] WP

Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in June 2006 due to hepatotoxicity leading to liver transplant or death.[2][3] WP

Chemistry

Awaiting sourceFormula, structure and identifiers from PubChem.

Harm reduction information

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Sources

  1. Journal / agency Center for Drug Evaluation and Research – Application Number: 020759/020760 – Chemistry Review(s)
  2. Journal / agency TROVAN® Tablets(trovafloxacin mesylate)TROVAN® I.V.(alatrofloxacin mesylate injection)For Intravenous Infusion
  3. Journal / agency Qureshi ZP, Seoane-Vazquez E, Rodriguez-Monguio R, Stevenson KB, Szeinbach SL. Market withdrawal of new molecular entities approved in the United States from 1980 to 2009. Pharmacoepidemiology and Drug Safety. July 2011. doi:10.1002/pds.2155 · PMID 21574210

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