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Substance

Telmisartan/amlodipine

Original Wikipedia articleen.wikipedia.org/wiki/Telmisartan/amlodipine revision used (24 October 2026)

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Overview

Telmisartan/amlodipine, sold under the brand name Twynsta among others, is a fixed-dose combination medication used to treat high blood pressure. It is a combination of telmisartan, an angiotensin II receptor antagonist; and amlodipine, as the besilate, a calcium channel blocker. It is taken by mouth.[1] WP

Common side effects include dizziness, swelling, and back pain. Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack. Use during pregnancy may harm the baby. Telmisartan works by blocking the effects of angiotensin II while amlodipine works by decreasing calcium ion entry into smooth muscle and heart muscle.[1] WP

The combination was approved for medical use in the United States in 2009. The combination is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.[1][2][3] WP

Chemistry

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Harm reduction information

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Sources

  1. Journal / agency DailyMed - Telmisartan and Amlodipine tablet
  2. Other The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). 2023
  3. Other Telmisartan and Amlodipine (Professional Patient Advice)

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