Psychoactive drug · Stimulant · Monoamine releasing agent · Monoamine oxidase inhibitor

Para-Ethoxyamphetamine

Also called 4-Ethoxyamphetamine

Original Wikipedia articleen.wikipedia.org/wiki/Para-Ethoxyamphetamine revision used (24 October 2026)

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Overview

para-Ethoxyamphetamine (PEtOA), also known as 4-ethoxyamphetamine (4-EA, 4-ETA, or 4-EtO-A), is a psychoactive drug of the phenethylamine and amphetamine families which is closely related to para-methoxyamphetamine (PMA). It has similar effects to PMA in animal studies, although with slightly weaker stimulant effects. Like PMA, it has prominent MAOI activity, and is likely to have similar dangers associated with its use.[1–4] WP

Drug class

Psychoactive drug Stimulant Monoamine releasing agent Monoamine oxidase inhibitor WP

From the Wikipedia article's infobox.

Chemistry

Formula: C11H17NO PC
CAS number: 129476-58-0 PC
Molar mass (g/mol): 179.26 PC
IUPAC name (computed by PubChem): 1-(4-ethoxyphenyl)propan-2-amine PC
SMILES: CCOC1=CC=C(C=C1)CC(C)N PC
InChIKey: CCAMEVFYMFXHEN-UHFFFAOYSA-N PC
PubChem CID: 125379
IUPAC name: 1-(4-ethoxyphenyl)propan-2-amine WP

Mixing

For best safety practice, don't mix this drug with other stimulants.

Why: vasoconstriction, heart rate and blood pressure. PsychonautWiki says:

“... may be dangerous to combine with other stimulants ... as they can increase one's heart rate and blood pressure to dangerous levels.” (PsychonautWiki, dangerous interactions table, "Stimulants" row, revision 148925)
“Vasoconstriction can be described as a narrowing of the veins and blood vessels which results from a contraction of their muscular wall.” (PsychonautWiki, Vasoconstriction, revision 170337)
“... it can also occur under the influence of traditional stimulants such as methamphetamine, caffeine, and MDMA.” (PsychonautWiki, Vasoconstriction, revision 170337)
“Increased blood pressure is most commonly induced under the influence of heavy dosages of vasoconstricting compounds, such as traditional stimulants and stimulating psychedelics.” (PsychonautWiki, Increased blood pressure, revision 152273)

Quotes from PsychonautWiki, CC BY-SA 4.0.

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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User reports

Erowid erowid.org

Listings

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Listings

Awaiting sourceTrip report threads and this substance's discussion forum.

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Pop culture

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Sources

Journal / agency Martin-Iverson MT, Yamada N, By AW, Lodge BA. "Designer" amphetamines: effects on behavior and monoamines with or without reserpine and/or alpha-methyl-para-tyrosine pretreatment. Journal of Psychiatry & Neuroscience. December 1991. PMID 1686728 · PMC1188362
Journal / agency Corrigall WA, Robertson JM, Coen KM, Lodge BA. The reinforcing and discriminative stimulus properties of para-ethoxy- and para-methoxyamphetamine. Pharmacology Biochemistry and Behavior. January 1992. doi:10.1016/0091-3057(92)90077-S · PMID 1539067
Journal / agency Hegadoren KM, Greenshaw AJ, Baker GB, Martin-Iverson MT, Lodge B, Soin S. 4-Ethoxyamphetamine: effects on intracranial self-stimulation and in vitro uptake and release of 3H-dopamine and 3H-serotonin in the brains of rats. Journal of Psychiatry & Neuroscience. January 1994. PMID 8148367 · PMC1188563
Journal / agency Martin-Iverson MT, Lodge BA. Effects of chronic treatment of rats with "designer" amphetamines on brain regional monoamines. Canadian Journal of Physiology and Pharmacology. December 1991. doi:10.1139/y91-270 · PMID 1802356

Text and values on this page are quoted from Wikipedia (CC BY-SA 4.0), PubChem (public domain). Each value links to the exact revision it came from.