Neohesperidin
Overview
ChEBI: Neohesperidin is a flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group.[1] PC
MeSH: antiulcer agent from the fruits of Poncirus trifoliata; structure in first source[2] PC
What studies say
Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.
“Neohesperidin, hesperidin, and naringin, active flavanone glycosides, were identified in Citrus seed extract.”[3] (Banjerdpongchai R et al., Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, abstract)
Chemistry
- Formula
- C28H34O15 PC
- CAS number
- 13241-33-3 PC
- Molar mass (g/mol)
- 610.6 PC
- IUPAC name (computed by PubChem)
- (
2S) PC- 7- [ ( 2S, 3R, 4S, 5S, 6R) - 4, 5- dihydroxy- 6- ( hydroxymethyl) - 3- [ ( 2S, 3R, 4R, 5R, 6S) - 3, 4, 5- trihydroxy- 6- methyloxan- 2- yl] oxyoxan- 2- yl] oxy- 5- hydroxy- 2- ( 3- hydroxy- 4- methoxyphenyl) - 2, 3- dihydrochromen- 4- one - SMILES
- C[
C@H] PC1[ C@@H] ( [ C@H] ( [ C@H] ( [ C@@H] ( O1) O[ C@@H] 2[ C@H] ( [ C@@H] ( [ C@H] ( O[ C@H] 2OC3=CC( =C4C( =O) C[ C@H] ( OC4=C3) C5=CC( =C( C=C5) OC) O) O) CO) O) O) O) O) O - InChIKey
- ARGKVCXINMKCAZ-
UZRWAPQLSA- PCN - PubChem CID
- 442439
Harm reduction information
No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.
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Sources
- Journal / agency ChEBI (Chemical Entities of Biological Interest, EMBL-EBI). Description text for Neohesperidin, as shown in the PubChem record (CID 442439), retrieved 10 November 2026. Licence: CC BY 4.0; quoted word for word
- Journal / agency MeSH (Medical Subject Headings, U.S. National Library of Medicine). Description text for Neohesperidin, as shown in the PubChem record (CID 442439), retrieved 10 November 2026. Licence: Public domain (U.S. government work); quoted word for word
- Journal / agency Banjerdpongchai R, Wudtiwai B, Khaw-On P, Rachakhom W, Duangnil N, Kongtawelert P. Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2016. doi:10.1007/s13277-015-3774-7 · PMID 26194866 · PMC4841854 · Open access, CC BY licence; quoted word for word
- Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 442439. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table