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Substance

Meloxicam/rizatriptan

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Overview

Meloxicam/rizatriptan, sold under the brand name Symbravo, is a fixed-dose combination medication used for the treatment of migraine. It is a combination of meloxicam, a nonsteroidal anti-inflammatory medication; and rizatriptan (as rizatriptan benzoate), a serotonin (5-HT) 1B/1D receptor agonist (triptan). It is taken by mouth.[1] WP

Meloxicam/rizatriptan was approved for medical use in the United States in January 2025.[2] WP

Uses, dosage and effects

Medical uses

Meloxicam/rizatriptan is indicated for the acute treatment of migraine with or without aura in adults.[1][3] WP

Chemistry

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Harm reduction information

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User reports

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Sources

  1. Journal / agency Symbravo- meloxicam, rizatriptan tablet. 24 February 2025
  2. Other Axsome Therapeutics Announces FDA Approval of Symbravo (meloxicam and rizatriptan) for the Acute Treatment of Migraine with or without Aura in Adults. 30 January 2025
  3. Journal / agency Karsan N, Goadsby PJ. New Oral Drugs for Migraine. CNS Drugs. September 2022. doi:10.1007/s40263-022-00948-8 · PMID 36031682 · PMC9477894

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