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Compound

L-Serine

Also called Serine

Overview

NCI Thesaurus: Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system.[1] PC

MeSH: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.[2] PC

What studies say

Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.

“Serine is the major source of one-carbon units for methylation reactions that occur via the generation of S-adenosylmethionine.”[3] (Kalhan SC et al., The Journal of biological chemistry, 2012, abstract)

Chemistry

Formula
C3H7NO3 PC
CAS number
56-45-1 PC
Molar mass (g/mol)
105.09 PC
IUPAC name (computed by PubChem)
(2S)-2-amino-3-hydroxypropanoic acid PC
SMILES
C([C@@H](C(=O)O)N)O PC
InChIKey
MTCFGRXMJLQNBG-REOHCLBHSA-N PC
PubChem CID
5951

Harm reduction information

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Sources

  1. Journal / agency NCI Thesaurus (U.S. National Cancer Institute). Description text for L-Serine, as shown in the PubChem record (CID 5951), retrieved 10 November 2026. Licence: Free of copyright, credit NCI; quoted word for word
  2. Journal / agency MeSH (Medical Subject Headings, U.S. National Library of Medicine). Description text for L-Serine, as shown in the PubChem record (CID 5951), retrieved 10 November 2026. Licence: Public domain (U.S. government work); quoted word for word
  3. Journal / agency Kalhan SC, Hanson RW. Resurgence of serine: an often neglected but indispensable amino Acid. The Journal of biological chemistry. 2012. doi:10.1074/jbc.r112.357194 · PMID 22566694 · PMC3370164 · Open access, CC BY licence; quoted word for word
  4. Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 5951. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table