intoxicant.wiki2catechol4school
Compound

J147

Also called J-147

Overview

MeSH: neurotrophic curcumin derivative compound that has enhanced stability and bioavailability over curcumin[1] PC

What studies say

Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.

“J147 is an Alzheimer's disease (AD) drug candidate that was identified using a phenotypic screening platform based upon age-related brain toxicities that are mediated by changes in calcium metabolism.”[2] (Goldberg J et al., NPJ aging and mechanisms of disease, 2020, abstract)

Chemistry

Formula
C18H17F3N2O2 PC
CAS number
1146963-51-0 PC
Molar mass (g/mol)
350.3 PC
IUPAC name (computed by PubChem)
N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide PC
SMILES
CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C PC
InChIKey
HYMZAYGFKNNHDN-SSDVNMTOSA-N PC
PubChem CID
25229652

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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User reports

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Sources

  1. Journal / agency MeSH (Medical Subject Headings, U.S. National Library of Medicine). Description text for J147, as shown in the PubChem record (CID 25229652), retrieved 10 November 2026. Licence: Public domain (U.S. government work); quoted word for word
  2. Journal / agency Goldberg J, Currais A, Ates G, Huang L, Shokhirev M, Maher P, Schubert D. Targeting of intracellular Ca<sup>2+</sup> stores as a therapeutic strategy against age-related neurotoxicities. NPJ aging and mechanisms of disease. 2020. doi:10.1038/s41514-020-00048-1 · PMID 32884834 · PMC7445274 · Open access, CC BY licence; quoted word for word
  3. Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 25229652. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table