intoxicant.wiki2catechol4school
Compound

Idebenone

Overview

ChEBI: Idebenone is a member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia.[1] PC

What studies say

Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.

“Idebenone is an antioxidant and a coenzyme Q10 analog that has been used to treat neurodegeneration disease.”[2] (Yan A et al., Frontiers in cellular neuroscience, 2018, abstract)

Chemistry

Formula
C19H30O5 PC
CAS number
58186-27-9 PC
Molar mass (g/mol)
338.4 PC
IUPAC name (computed by PubChem)
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione PC
SMILES
CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO PC
InChIKey
JGPMMRGNQUBGND-UHFFFAOYSA-N PC
PubChem CID
3686

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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User reports

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Sources

  1. Journal / agency ChEBI (Chemical Entities of Biological Interest, EMBL-EBI). Description text for Idebenone, as shown in the PubChem record (CID 3686), retrieved 10 November 2026. Licence: CC BY 4.0; quoted word for word
  2. Journal / agency Yan A, Liu Z, Song L, Wang X, Zhang Y, Wu N, Lin J, Liu Y, Liu Z. Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson's Disease Mice. Frontiers in cellular neuroscience. 2018. doi:10.3389/fncel.2018.00529 · PMID 30687016 · PMC6333870 · Open access, CC BY licence; quoted word for word
  3. Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 3686. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table